Revisiting demographic processes in cattle with genome-wide population genetic analysis
Name
Revisiting_demographic_processes_in_cattle_with_genome-wide_population_genetic_analysis.pdf
Description
visibility:open
Size
1.74 MB
Format
Adobe PDF
Checksum (CRC64NVME)
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Resource type
Journal article
Creator (person)
Orozco-terWengel, Pablo
Barbato, Mario
Nicolazzi, Ezequiel
Biscarini, Filippo
Milanesi, Marco
Davies, Wyn
Williams, Don
Stella, Alessandra
Ajmone-Marsan, Paolo
Bruford, Michael W.
Date published
June 2, 2015
Abstract
The domestication of the aurochs took place approximately 10,000 years ago giving rise to the two main types of domestic cattle known today, taurine (Bos taurus) domesticated somewhere on or near the Fertile Crescent, and indicine (Bos indicus) domesticated in the Indus Valley. However, although cattle have historically played a prominent role in human society the exact origin of many extant breeds is not well known. Here we used a combination of medium and high-density Illumina Bovine SNP arrays (i.e., ~54,000 and ~770,000 SNPs, respectively), genotyped for over 1300 animals representing 56 cattle breeds, to describe the relationships among major European cattle breeds and detect patterns of admixture among them. Our results suggest modern cross-breeding and ancient hybridisation events have both played an important role, including with animals of indicine origin. We use these data to identify signatures of selection reflecting both domestication (hypothesized to produce a common signature across breeds) and local adaptation (predicted to exhibit a signature of selection unique to a single breed or group of related breeds with a common history) to uncover additional demographic complexity of modern European cattle.
Journal title
Frontiers in Genetics
Volume
6
Issue
JUN
Article number
191
Publisher
Frontiers Media SA
eISSN
1664-8021
Official URL
Rights statement
In Copyright